- 产品信息
商品描述
靶点-Target
GRK 3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GRK3. AA range:361-410
特异性
GRK 3 Polyclonal Antibody detects endogenous levels of GRK 3 protein.
基因名称
ADRBK2
蛋白名称
Beta-adrenergic receptor kinase 2
别名
ADRBK2;BARK2;GRK3;Beta-adrenergic receptor kinase 2;Beta-ARK-2;G-protein-coupled receptor kinase 3
Organism-1
Human
基因ID-1
157
SwissProt-1
P35626
Organism-2
Mouse
基因ID-2
320129
SwissProt-2
Q3UYH7
Organism-3
Rat
基因ID-3
25372
SwissProt-3
P26819
背景
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .





