- 产品信息
商品描述
靶点-Target
GRK1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
63kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GRK1. AA range:6-55
特异性
GRK 1 Polyclonal Antibody detects endogenous levels of GRK 1 protein.
基因名称
GRK1
蛋白名称
Rhodopsin kinase
别名
GRK1;RHOK;Rhodopsin kinase;RK;G protein-coupled receptor kinase 1
Organism-1
Human
基因ID-1
6011
SwissProt-1
Q15835
Organism-2
Mouse
SwissProt-2
Q9WVL4
Organism-3
Rat
基因ID-3
81760
SwissProt-3
Q63651
背景
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Lipid-anchor . Cell projection, cilium, photoreceptor outer segment . Subcellular location is not affected by light or dark conditions. .





