FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GRIP-1
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
159kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NCoA2. AA range:702-751
特异性
GRIP-1 Polyclonal Antibody detects endogenous levels of GRIP-1 protein.
基因名称
NCOA2
蛋白名称
Nuclear receptor coactivator 2
别名
NCOA2;BHLHE75;TIF2;Nuclear receptor coactivator 2;NCoA-2;Class E basic helix-loop-helix protein 75;bHLHe75;Transcriptional intermediary factor 2;hTIF2
Organism-1
Human
基因ID-1
10499
SwissProt-1
Q15596
Organism-2
Mouse
SwissProt-2
Q61026
背景
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Nucleus .
