GRB2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614359

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商品描述
  • 靶点-Target

    GRB2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    32kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human GRB2. AA range:141-190

  • 特异性

    GRB2 Polyclonal Antibody detects endogenous levels of GRB2 protein.

  • 基因名称

    GRB2

  • 蛋白名称

    Growth factor receptor-bound protein 2

  • 别名

    GRB2;ASH;Growth factor receptor-bound protein 2;Adapter protein GRB2;Protein Ash;SH2/SH3 adapter GRB2

  • Organism-1

    Human

  • 基因ID-1

    2885

  • SwissProt-1

    P62993

  • Organism-2

    Mouse

  • 基因ID-2

    14784

  • SwissProt-2

    Q60631

  • Organism-3

    Rat

  • 基因ID-3

    81504

  • SwissProt-3

    P62994

  • 背景

    The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus . Cytoplasm . Endosome . Golgi apparatus .