FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Grap
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GRAP. AA range:1-50
特异性
Grap Polyclonal Antibody detects endogenous levels of Grap protein.
基因名称
GRAP
蛋白名称
GRB2-related adapter protein
别名
GRAP;GRB2-related adapter protein
Organism-1
Human
基因ID-1
10750
SwissProt-1
Q13588
Organism-2
Mouse
基因ID-2
71520
SwissProt-2
Q9CX99
背景
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012],
细胞定位
Membrane ; Peripheral membrane protein . Cell junction, synapse . Localizes at the presynaptic terminal. .
