FGF-2 Polyclonal Antibody
¥680.00
Granzyme B/H Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614352
- 产品信息
商品描述
靶点-Target
Granzyme B/H
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Granzyme B. AA range:10-59
特异性
Granzyme B/H Polyclonal Antibody detects endogenous levels of Granzyme B/H protein.
基因名称
GZMB/GZMH
蛋白名称
Granzyme B/H
别名
GZMB;CGL1;CSPB;CTLA1;GRB;Granzyme B;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E;GZMH;C
Organism-1
Human
基因ID-1
2999
SwissProt-1
P10144;P20718
Organism-2
Mouse
基因ID-2
14939
Organism-3
Rat
基因ID-3
#N/A
SwissProt-3
P18291
背景
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],
细胞定位
Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
