- 产品信息
商品描述
靶点-Target
GPT2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from GPT2 . at AA range: 190-270
特异性
GPT2 Polyclonal Antibody detects endogenous levels of GPT2 protein.
基因名称
GPT2
蛋白名称
Alanine aminotransferase 2
别名
GPT2;AAT2;ALT2;Alanine aminotransferase 2;ALT2;Glutamate pyruvate transaminase 2;GPT 2;Glutamic--alanine transaminase 2;Glutamic--pyruvic transaminase 2
Organism-1
Human
基因ID-1
84706
SwissProt-1
Q8TD30
Organism-2
Mouse
SwissProt-2
Q8BGT5
背景
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
细胞定位
mitochondrion,mitochondrial matrix,





