FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GPR56
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
78kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300
特异性
GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.
基因名称
GPR56
蛋白名称
G-protein coupled receptor 56
别名
GPR56;TM7LN4;TM7XN1;G-protein coupled receptor 56;Protein TM7XN1
Organism-1
Human
基因ID-1
9289
SwissProt-1
Q9Y653
Organism-2
Mouse
SwissProt-2
Q8K209
背景
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
细胞定位
Cell membrane ; Multi-pass membrane protein .; [ADGRG1 N-terminal fragment]: Secreted .; [ADGRG1 C-terminal fragment]: Membrane raft . Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. .
