- 产品信息
商品描述
靶点-Target
GPR172A
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92
特异性
GPR172A Polyclonal Antibody detects endogenous levels of GPR172A protein.
基因名称
SLC52A2
蛋白名称
Solute carrier family 52 riboflavin transporter member 2
别名
SLC52A2;GPR172A;PAR1;RFT3;Solute carrier family 52;riboflavin transporter, member 2;Porcine endogenous retrovirus A receptor 1;PERV-A receptor 1;Protein GPR172A;Riboflavin transporter 3;hRFT3
Organism-1
Human
基因ID-1
79581
SwissProt-1
Q9HAB3
Organism-2
Mouse
SwissProt-2
Q9D8F3
背景
This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunctio
细胞定位
Cell membrane ; Multi-pass membrane protein .





