FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GPR143
反应性
Human,Mouse
应用
IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
44kD
推荐稀释比
IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200
特异性
GPR143 Polyclonal Antibody detects endogenous levels of GPR143 protein.
基因名称
GPR143
蛋白名称
G-protein coupled receptor 143
别名
GPR143;OA1;G-protein coupled receptor 143;Ocular albinism type 1 protein
Organism-1
Human
基因ID-1
4935
SwissProt-1
P51810
Organism-2
Mouse
基因ID-2
18241
SwissProt-2
P70259
背景
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009],
细胞定位
Melanosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
