FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GnRH-R
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
37kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GNRHR. AA range:41-90
特异性
GnRH-R Polyclonal Antibody detects endogenous levels of GnRH-R protein.
基因名称
GNRHR
蛋白名称
Gonadotropin-releasing hormone receptor
别名
GNRHR;GRHR;Gonadotropin-releasing hormone receptor;GnRH receptor;GnRH-R
Organism-1
Human
基因ID-1
2798
SwissProt-1
P30968
Organism-2
Mouse
基因ID-2
14715
SwissProt-2
Q01776
背景
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gen
细胞定位
Cell membrane; Multi-pass membrane protein.
