- 产品信息
商品描述
靶点-Target
GluR-5
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GluR5. AA range:10-59
特异性
GluR-5 Polyclonal Antibody detects endogenous levels of GluR-5 protein.
基因名称
GRIK1
蛋白名称
Glutamate receptor ionotropic kainate 1
别名
GRIK1;GLUR5;Glutamate receptor;ionotropic kainate 1;Excitatory amino acid receptor 3;EAA3;Glutamate receptor 5;GluR-5;GluR5
Organism-1
Human
基因ID-1
2897
SwissProt-1
P39086
Organism-2
Mouse
SwissProt-2
Q60934
Organism-3
Rat
基因ID-3
29559
SwissProt-3
P22756
背景
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.





