FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GLP1R
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
53kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GLP1R. AA range:101-150
特异性
GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.
基因名称
GLP1R
蛋白名称
Glucagon-like peptide 1 receptor
别名
GLP1R;Glucagon-like peptide 1 receptor;GLP-1 receptor;GLP-1-R;GLP-1R
Organism-1
Human
基因ID-1
2740
SwissProt-1
P43220
Organism-2
Mouse
SwissProt-2
O35659
背景
glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein .
