- 产品信息
商品描述
靶点-Target
GCS-β-2
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102
特异性
GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.
基因名称
GUCY1B2
蛋白名称
Guanylate cyclase soluble subunit beta-2
别名
GUCY1B2;Guanylate cyclase soluble subunit beta-2;GCS-beta-2
Organism-1
Human
基因ID-1
2974
SwissProt-1
O75343
Organism-3
Rat
基因ID-3
25206
SwissProt-3
P22717
背景
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.
细胞定位
Cytoplasm.





