FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GCSm-γ
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
31kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GCSm-gamma. AA range:42-91
特异性
GCSm-γ Polyclonal Antibody detects endogenous levels of GCSm-γ protein.
基因名称
GCLM
蛋白名称
Glutamate--cysteine ligase regulatory subunit
别名
GCLM;GLCLR;Glutamate--cysteine ligase regulatory subunit;GCS light chain;Gamma-ECS regulatory subunit;Gamma-glutamylcysteine synthetase regulatory subunit;Glutamate--cysteine ligase modifier subunit
Organism-1
Human
基因ID-1
2730
SwissProt-1
P48507
Organism-2
Mouse
基因ID-2
14630
SwissProt-2
O09172
Organism-3
Rat
基因ID-3
29739
SwissProt-3
P48508
背景
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
细胞定位
cytosol,glutamate-cysteine ligase complex,
