FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GCSc-γ
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
73kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GCSc-gamma. AA range:266-315
特异性
GCSc-γ Polyclonal Antibody detects endogenous levels of GCSc-γ protein.
基因名称
GCLC
蛋白名称
Glutamate--cysteine ligase catalytic subunit
别名
GCLC;GLCL;GLCLC;Glutamate--cysteine ligase catalytic subunit;GCS heavy chain;Gamma-ECS;Gamma-glutamylcysteine synthetase
Organism-1
Human
基因ID-1
2729
SwissProt-1
P48506
Organism-2
Mouse
基因ID-2
14629
SwissProt-2
P97494
Organism-3
Rat
基因ID-3
25283
SwissProt-3
P19468
背景
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],
细胞定位
cytosol,integral component of membrane,glutamate-cysteine ligase complex,
