FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GCP4
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
76kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TUBGCP4. AA range:191-240
特异性
GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.
基因名称
TUBGCP4
蛋白名称
Gamma-tubulin complex component 4
别名
TUBGCP4;76P;GCP4;Gamma-tubulin complex component 4;GCP-4;hGCP4;Gamma-ring complex protein 76 kDa;h76p;hGrip76
Organism-1
Human
基因ID-1
27229
SwissProt-1
Q9UGJ1
Organism-2
Mouse
基因ID-2
51885
SwissProt-2
Q9D4F8
背景
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
