FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GCKR
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
68kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260
特异性
GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.
基因名称
GCKR
蛋白名称
Glucokinase regulatory protein
别名
GCKR;Glucokinase regulatory protein;Glucokinase regulator
Organism-1
Human
基因ID-1
2646
SwissProt-1
Q14397
Organism-2
Mouse
基因ID-2
231103
SwissProt-2
Q91X44
Organism-3
Rat
基因ID-3
25658
SwissProt-3
Q07071
背景
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
