- 产品信息
商品描述
靶点-Target
GBDR1
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140
特异性
GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.
基因名称
UBAC1
蛋白名称
Ubiquitin-associated domain-containing protein 1
别名
UBAC1;GBDR1;KPC2;UBADC1;Ubiquitin-associated domain-containing protein 1;UBA domain-containing protein 1;E3 ubiquitin-protein ligase subunit KPC2;Glialblastoma cell differentiation-related protein 1;Kip1 ubiquitination-promoting com
Organism-1
Human
基因ID-1
10422
SwissProt-1
Q9BSL1
Organism-2
Mouse
SwissProt-2
Q8VDI7
背景
function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,
细胞定位
Cytoplasm .





