- 产品信息
商品描述
靶点-Target
GASP-1
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
157kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790
特异性
GASP-1 Polyclonal Antibody detects endogenous levels of GASP-1 protein.
基因名称
GPRASP1
蛋白名称
G-protein coupled receptor-associated sorting protein 1
别名
GPRASP1;GASP;KIAA0443;G-protein coupled receptor-associated sorting protein 1;GASP-1
Organism-1
Human
基因ID-1
9737
SwissProt-1
Q5JY77
Organism-2
Mouse
SwissProt-2
Q5U4C1
背景
This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010],
细胞定位
Cytoplasm .





