GalNAc4ST-1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614170

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商品描述
  • 靶点-Target

    GalNAc4ST-1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    40kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CHST8. AA range:341-390

  • 特异性

    GalNAc4ST-1 Polyclonal Antibody detects endogenous levels of GalNAc4ST-1 protein.

  • 基因名称

    CHST8

  • 蛋白名称

    Carbohydrate sulfotransferase 8

  • 别名

    CHST8;Carbohydrate sulfotransferase 8;GalNAc-4-O-sulfotransferase 1;GalNAc-4-ST1;GalNAc4ST-1;N-acetylgalactosamine-4-O-sulfotransferase 1

  • Organism-1

    Human

  • 基因ID-1

    64377

  • SwissProt-1

    Q9H2A9

  • Organism-2

    Mouse

  • 基因ID-2

    68947

  • SwissProt-2

    Q8BQ86

  • 背景

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011],

  • 细胞定位

    Golgi apparatus membrane ; Single-pass type II membrane protein .