FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GAD67
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
67kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GAD1. AA range:471-520
特异性
GAD67 Polyclonal Antibody detects endogenous levels of GAD67 protein.
基因名称
GAD1
蛋白名称
Glutamate decarboxylase 1
别名
GAD1;GAD;GAD67;Glutamate decarboxylase 1;67 kDa glutamic acid decarboxylase;GAD-67;Glutamate decarboxylase 67 kDa isoform
Organism-1
Human
基因ID-1
2571
SwissProt-1
Q99259
Organism-2
Mouse
基因ID-2
14415
SwissProt-2
P48318
Organism-3
Rat
基因ID-3
24379
SwissProt-3
P18088
背景
glutamate decarboxylase 1(GAD1) Homo sapiens This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008],
细胞定位
intracellular,plasma membrane,vesicle membrane,presynaptic active zone,clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane,
