FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GABAB R1
反应性
Human,Mouse,Rat,Guinea Pig
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
108kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GABBR1. AA range:891-940
特异性
GABAB R1 Polyclonal Antibody detects endogenous levels of GABAB R1 protein.
基因名称
GABBR1
蛋白名称
Gamma-aminobutyric acid type B receptor subunit 1
别名
GABBR1;GPRC3A;Gamma-aminobutyric acid type B receptor subunit 1;GABA-B receptor 1;GABA-B-R1;GABA-BR1;GABABR1;Gb1
Organism-1
Human
基因ID-1
2550
SwissProt-1
Q9UBS5
Organism-2
Mouse
基因ID-2
54393
SwissProt-2
Q9WV18
Organism-3
Rat
基因ID-3
81657
SwissProt-3
Q9Z0U4
背景
This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512). .; [Isoform 1E]: Secreted .
