FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GABRD
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
51kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
特异性
GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
基因名称
GABRD
蛋白名称
Gamma-aminobutyric acid receptor subunit delta
别名
GABRD;Gamma-aminobutyric acid receptor subunit delta;GABA;A;receptor subunit delta
Organism-1
Human
基因ID-1
2563
SwissProt-1
O14764
Organism-2
Mouse
基因ID-2
14403
SwissProt-2
P22933
Organism-3
Rat
基因ID-3
29689
SwissProt-3
P18506
背景
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
