FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FucT-III
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FUT3. AA range:91-140
特异性
FucT-III Polyclonal Antibody detects endogenous levels of FucT-III protein.
基因名称
FUT3
蛋白名称
Galactoside 3(4)-L-fucosyltransferase
别名
FUT3;FT3B;LE;Galactoside 3;4;-L-fucosyltransferase;Blood group Lewis alpha-4-fucosyltransferase;Lewis FT;Fucosyltransferase 3;Fucosyltransferase III;FucT-III
Organism-1
Human
基因ID-1
2525
SwissProt-1
P21217
背景
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein . Membrane-bound form in trans cisternae of Golgi.
