FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FR-α
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FOLR1. AA range:41-90
特异性
FR-α Polyclonal Antibody detects endogenous levels of FR-α protein.
基因名称
FOLR1
蛋白名称
Folate receptor alpha
别名
FOLR1;FOLR;Folate receptor alpha;FR-alpha;Adult folate-binding protein;FBP;Folate receptor 1;Folate receptor;adult;KB cells FBP;Ovarian tumor-associated antigen MOv18
Organism-1
Human
基因ID-1
2348
SwissProt-1
P15328
Organism-2
Mouse
SwissProt-2
P35846
背景
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009],
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor . Apical cell membrane ; Lipid-anchor, GPI-anchor . Basolateral cell membrane ; Lipid-anchor, GPI-like-anchor . Secreted . Cytoplasmic vesicle . Cytoplasmic vesicle, clathrin-coated vesicle . Endosome . Endocytosed into cytoplasmic vesicles and then recycled to the cell membrane. .
