Frizzled-8 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2614124
- 产品信息
商品描述
靶点-Target
Frizzled-8
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535
特异性
Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.
基因名称
FZD8
蛋白名称
Frizzled-8
别名
FZD8;Frizzled-8;Fz-8;hFz8
Organism-1
Human
基因ID-1
8325
SwissProt-1
Q9H461
Organism-2
Mouse
基因ID-2
14370
SwissProt-2
Q61091
Organism-3
Rat
基因ID-3
100909849
SwissProt-3
Q498S8
背景
frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Multi-pass membrane protein. Golgi apparatus . Cell membrane ; Multi-pass membrane protein . Colocalizes with GOPC at the Golgi apparatus. .





