FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FoxC1/2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FOXC1/2. AA range:151-200
特异性
FoxC1/2 Polyclonal Antibody detects endogenous levels of FoxC1/2 protein.
基因名称
FOXC1/FOXC2
蛋白名称
Forkhead box protein C1/2
别名
FOXC1;FKHL7;FREAC3;Forkhead box protein C1;Forkhead-related protein FKHL7;Forkhead-related transcription factor 3;FREAC-3;FOXC2;FKHL14;MFH1;Forkhead box protein C2;Forkhead-related protein FKHL14;Mesenchyme fork head protein 1;
Organism-1
Human
基因ID-1
2296;2303
SwissProt-1
Q12948;Q99958
Organism-2
Mouse
基因ID-2
17300;14234
Organism-3
Rat
SwissProt-3
Q63246
背景
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Colocalizes with PITX2 isoform 3 in the nucleus at subnuclear chromatine regions (PubMed:16449236). Colocalizes with CBX5 to a heterochromatin-rich region of the nucleus (PubMed:15684392). Colocalizes with GLI2 in the nucleus (By similarity). .
