FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FIR
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
119kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
特异性
FIR Polyclonal Antibody detects endogenous levels of FIR protein.
基因名称
FARP2
蛋白名称
FERM RhoGEF and pleckstrin domain-containing protein 2
别名
FARP2;KIAA0793;PLEKHC3;FERM;RhoGEF and pleckstrin domain-containing protein 2;FERM domain including RhoGEF;FIR;Pleckstrin homology domain-containing family C member 3;PH domain-containing family C member 3
Organism-1
Human
基因ID-1
9855
SwissProt-1
O94887
Organism-2
Mouse
基因ID-2
227377
SwissProt-2
Q91VS8
背景
function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,
细胞定位
cytoplasm,cytosol,cytoskeleton,extrinsic component of membrane,
