FGF-2 Polyclonal Antibody
¥680.00
Fibulin-5 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614063
- 产品信息
商品描述
靶点-Target
Fibulin-5
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220
特异性
Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.
基因名称
FBLN5
蛋白名称
Fibulin-5
别名
FBLN5;DANCE;Fibulin-5;FIBL-5;Developmental arteries and neural crest EGF-like protein;Dance;Urine p50 protein;UP50
Organism-1
Human
基因ID-1
10516
SwissProt-1
Q9UBX5
Organism-2
Mouse
基因ID-2
23876
SwissProt-2
Q9WVH9
Organism-3
Rat
基因ID-3
29158
SwissProt-3
Q9WVH8
背景
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Secreted, extracellular space, extracellular matrix . co-localizes with ELN in elastic fibers. .
