FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FGFR-5
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
54kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from FGFR-5 . at AA range: 130-210
特异性
FGFR-5 Polyclonal Antibody detects endogenous levels of FGFR-5 protein.
基因名称
FGFRL1
蛋白名称
Fibroblast growth factor receptor-like 1
别名
FGFRL1;FGFR5;FHFR;Fibroblast growth factor receptor-like 1;FGF receptor-like protein 1;FGF homologous factor receptor;FGFR-like protein;Fibroblast growth factor receptor 5;FGFR-5
Organism-1
Human
基因ID-1
53834
SwissProt-1
Q8N441
Organism-2
Mouse
基因ID-2
116701
SwissProt-2
Q91V87
背景
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other
细胞定位
Membrane ; Single-pass type I membrane protein . Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
