- 产品信息
商品描述
靶点-Target
FGF-23
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200
特异性
FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.
基因名称
FGF23
蛋白名称
Fibroblast growth factor 23
别名
FGF23;HYPF;Fibroblast growth factor 23;FGF-23;Phosphatonin;Tumor-derived hypophosphatemia-inducing factor
Organism-1
Human
基因ID-1
8074
SwissProt-1
Q9GZV9
Organism-2
Mouse
基因ID-2
64654
SwissProt-2
Q9EPC2
Organism-3
Rat
基因ID-3
170583
SwissProt-3
Q8VI82
背景
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013],
细胞定位
Secreted . Secretion is dependent on O-glycosylation.





