- 产品信息
商品描述
靶点-Target
FAST
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
61kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410
特异性
FAST Polyclonal Antibody detects endogenous levels of FAST protein.
基因名称
FASTK
蛋白名称
Fas-activated serine/threonine kinase
别名
FASTK;Fas-activated serine/threonine kinase;FAST kinase
Organism-1
Human
基因ID-1
10922
SwissProt-1
Q14296
Organism-2
Mouse
SwissProt-2
Q9JIX9
背景
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 4]: Mitochondrion matrix . Colocalizes with mitochondrial RNA granules. .





