FAST Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614033

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商品描述
  • 靶点-Target

    FAST

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    61kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410

  • 特异性

    FAST Polyclonal Antibody detects endogenous levels of FAST protein.

  • 基因名称

    FASTK

  • 蛋白名称

    Fas-activated serine/threonine kinase

  • 别名

    FASTK;Fas-activated serine/threonine kinase;FAST kinase

  • Organism-1

    Human

  • 基因ID-1

    10922

  • SwissProt-1

    Q14296

  • Organism-2

    Mouse

  • SwissProt-2

    Q9JIX9

  • 背景

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],

  • 细胞定位

    [Isoform 4]: Mitochondrion matrix . Colocalizes with mitochondrial RNA granules. .