Factor XIII B Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614019

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商品描述
  • 靶点-Target

    Factor XIII B

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    80kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human F13B. AA range:61-110

  • 特异性

    Factor XIII B Polyclonal Antibody detects endogenous levels of Factor XIII B protein.

  • 基因名称

    F13B

  • 蛋白名称

    Coagulation factor XIII B chain

  • 别名

    F13B;Coagulation factor XIII B chain;Fibrin-stabilizing factor B subunit;Protein-glutamine gamma-glutamyltransferase B chain;Transglutaminase B chain

  • Organism-1

    Human

  • 基因ID-1

    2165

  • SwissProt-1

    P05160

  • Organism-2

    Mouse

  • SwissProt-2

    Q07968

  • 背景

    This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classi

  • 细胞定位

    Secreted .