FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ETO-2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
71kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MTG16. AA range:261-310
特异性
ETO-2 Polyclonal Antibody detects endogenous levels of ETO-2 protein.
基因名称
CBFA2T3
蛋白名称
Protein CBFA2T3
别名
CBFA2T3;MTG16;MTGR2;ZMYND4;Protein CBFA2T3;MTG8-related protein 2;Myeloid translocation gene on chromosome 16 protein;hMTG16;Zinc finger MYND domain-containing protein 4
Organism-1
Human
基因ID-1
863
SwissProt-1
O75081
Organism-2
Mouse
基因ID-2
12398
SwissProt-2
O54972
背景
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],
细胞定位
[Isoform 1]: Nucleus, nucleolus. The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm.; [Isoform 2]: Nucleus, nucleoplasm . Golgi apparatus membrane .
