- 产品信息
商品描述
靶点-Target
ETAR
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EDNRA. AA range:378-427
特异性
ETAR Polyclonal Antibody detects endogenous levels of ETAR protein.
基因名称
EDNRA
蛋白名称
Endothelin-1 receptor
别名
EDNRA;ETA;ETRA;Endothelin-1 receptor;Endothelin A receptor;ET-A;ETA-R;hET-AR
Organism-1
Human
基因ID-1
1909
SwissProt-1
P25101
Organism-2
Mouse
基因ID-2
13617
SwissProt-2
Q61614
背景
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
细胞定位
Cell membrane; Multi-pass membrane protein.





