FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Estrogen Receptor-β
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
59kD
推荐稀释比
WB 1:500-2000;IF 1:50-300;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta. AA range:71-120
特异性
ERβ Polyclonal Antibody detects endogenous levels of ERβ protein.
基因名称
ESR2
蛋白名称
Estrogen receptor beta
别名
ESR2;ESTRB;NR3A2;Estrogen receptor beta;ER-beta;Nuclear receptor subfamily 3 group A member 2
Organism-1
Human
基因ID-1
2100
SwissProt-1
Q92731
Organism-2
Mouse
基因ID-2
13983
SwissProt-2
O08537
Organism-3
Rat
基因ID-3
25149
SwissProt-3
Q62986
背景
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .
