- 产品信息
商品描述
靶点-Target
ERCC4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
103kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
特异性
ERCC4 Polyclonal Antibody detects endogenous levels of ERCC4 protein.
基因名称
ERCC4
蛋白名称
DNA repair endonuclease XPF
别名
ERCC4;ERCC11;XPF;DNA repair endonuclease XPF;DNA excision repair protein ERCC-4;DNA repair protein complementing XP-F cells;Xeroderma pigmentosum group F-complementing protein
Organism-1
Human
基因ID-1
2072
SwissProt-1
Q92889
Organism-2
Mouse
基因ID-2
50505
SwissProt-2
Q9QZD4
背景
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009],
细胞定位
Nucleus . Chromosome . Localizes to sites of DNA damage. .





