- 产品信息
商品描述
靶点-Target
ERAP1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
107kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARTS-1. AA range:441-490
特异性
ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.
基因名称
ERAP1
蛋白名称
Endoplasmic reticulum aminopeptidase 1
别名
ERAP1;APPILS;ARTS1;KIAA0525;Endoplasmic reticulum aminopeptidase 1;ARTS-1;Adipocyte-derived leucine aminopeptidase;A-LAP;Aminopeptidase PILS;Puromycin-insensitive leucyl-specific aminopeptidase;PILS-AP;Type 1 tumor necrosis facto
Organism-1
Human
基因ID-1
51752
SwissProt-1
Q9NZ08
Organism-2
Mouse
基因ID-2
80898
SwissProt-2
Q9EQH2
Organism-3
Rat
基因ID-3
80897
SwissProt-3
Q9JJ22
背景
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .





