ERAP1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613986

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商品描述
  • 靶点-Target

    ERAP1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    107kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ARTS-1. AA range:441-490

  • 特异性

    ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.

  • 基因名称

    ERAP1

  • 蛋白名称

    Endoplasmic reticulum aminopeptidase 1

  • 别名

    ERAP1;APPILS;ARTS1;KIAA0525;Endoplasmic reticulum aminopeptidase 1;ARTS-1;Adipocyte-derived leucine aminopeptidase;A-LAP;Aminopeptidase PILS;Puromycin-insensitive leucyl-specific aminopeptidase;PILS-AP;Type 1 tumor necrosis facto

  • Organism-1

    Human

  • 基因ID-1

    51752

  • SwissProt-1

    Q9NZ08

  • Organism-2

    Mouse

  • 基因ID-2

    80898

  • SwissProt-2

    Q9EQH2

  • Organism-3

    Rat

  • 基因ID-3

    80897

  • SwissProt-3

    Q9JJ22

  • 背景

    The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],

  • 细胞定位

    Endoplasmic reticulum membrane ; Single-pass type II membrane protein .