- 产品信息
商品描述
靶点-Target
ERAB
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ERAB. AA range:111-160
特异性
ERAB Polyclonal Antibody detects endogenous levels of ERAB protein.
基因名称
HSD17B10
蛋白名称
3-hydroxyacyl-CoA dehydrogenase type-2
别名
HSD17B10;ERAB;HADH2;MRPP2;SCHAD;XH98G2;3-hydroxyacyl-CoA dehydrogenase type-2;17-beta-hydroxysteroid dehydrogenase 10;17-beta-HSD 10;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;3-hydroxyacyl-CoA dehydrogenase type II;Endoplasmic
Organism-1
Human
基因ID-1
3028
SwissProt-1
Q99714
Organism-2
Mouse
SwissProt-2
O08756
Organism-3
Rat
基因ID-3
63864
SwissProt-3
O70351
背景
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014],
细胞定位
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .





