ERAB Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2613985

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商品描述
  • 靶点-Target

    ERAB

  • 反应性

    Human,Mouse,Rat,Monkey

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    27kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ERAB. AA range:111-160

  • 特异性

    ERAB Polyclonal Antibody detects endogenous levels of ERAB protein.

  • 基因名称

    HSD17B10

  • 蛋白名称

    3-hydroxyacyl-CoA dehydrogenase type-2

  • 别名

    HSD17B10;ERAB;HADH2;MRPP2;SCHAD;XH98G2;3-hydroxyacyl-CoA dehydrogenase type-2;17-beta-hydroxysteroid dehydrogenase 10;17-beta-HSD 10;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;3-hydroxyacyl-CoA dehydrogenase type II;Endoplasmic

  • Organism-1

    Human

  • 基因ID-1

    3028

  • SwissProt-1

    Q99714

  • Organism-2

    Mouse

  • SwissProt-2

    O08756

  • Organism-3

    Rat

  • 基因ID-3

    63864

  • SwissProt-3

    O70351

  • 背景

    This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014],

  • 细胞定位

    Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .