- 产品信息
商品描述
靶点-Target
Epsin 1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Epsin 1 . at AA range: 140-220
特异性
Epsin 1 Polyclonal Antibody detects endogenous levels of Epsin 1 protein.
基因名称
EPN1
蛋白名称
Epsin-1
别名
EPN1;Epsin-1;EH domain-binding mitotic phosphoprotein;EPS-15-interacting protein 1
Organism-1
Human
基因ID-1
29924
SwissProt-1
Q9Y6I3
Organism-2
Mouse
基因ID-2
13854
SwissProt-2
Q80VP1
Organism-3
Rat
基因ID-3
117277
SwissProt-3
O88339
背景
This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016],
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein . Nucleus . Membrane, clathrin-coated pit . Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity). .





