Ephrin-B3 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2613976
- 产品信息
商品描述
靶点-Target
Ephrin-B3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EFNB3. AA range:221-270
特异性
Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.
基因名称
EFNB3
蛋白名称
Ephrin-B3
别名
EFNB3;EPLG8;LERK8;Ephrin-B3;EPH-related receptor transmembrane ligand ELK-L3;EPH-related receptor tyrosine kinase ligand 8;LERK-8
Organism-1
Human
基因ID-1
1949
SwissProt-1
Q15768
Organism-2
Mouse
基因ID-2
13643
SwissProt-2
O35393
背景
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the
细胞定位
Membrane; Single-pass type I membrane protein.





