FGF-2 Polyclonal Antibody
¥680.00
EphA2/3/4 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2613956
- 产品信息
商品描述
靶点-Target
EphA2/3/4
反应性
Human,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EPHA2/3/4. AA range:556-605
特异性
EphA2/3/4 Polyclonal Antibody detects endogenous levels of EphA2/3/4 protein.
基因名称
EPHA2/3/4
蛋白名称
Ephrin type-A receptor 2/3/4
别名
EPHA2;ECK;Ephrin type-A receptor 2;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK;EPHA3;ETK;ETK1;HEK;TYRO4;Ephrin type-A receptor 3;EPH-like kinase 4;EK4;hEK4;HEK;Human embryo kinase;Tyrosine-protein kinase TYRO
Organism-1
Human
基因ID-1
1969;2042;2043
SwissProt-1
P29317;P29320;P54764
Organism-3
Rat
基因ID-3
29210
SwissProt-3
O08680
背景
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .
