FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Epac
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761
特异性
Epac Polyclonal Antibody detects endogenous levels of Epac protein.
基因名称
RAPGEF3
蛋白名称
Rap guanine nucleotide exchange factor 3
别名
RAPGEF3;CGEF1;EPAC;EPAC1;Rap guanine nucleotide exchange factor 3;Exchange factor directly activated by cAMP 1;Exchange protein directly activated by cAMP 1;EPAC 1;Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;
Organism-1
Human
基因ID-1
10411
SwissProt-1
O95398
Organism-2
Mouse
基因ID-2
223864
SwissProt-2
Q8VCC8
Organism-3
Rat
基因ID-3
59326
SwissProt-3
Q9Z1C8
背景
caution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,
细胞定位
Endomembrane system .
