- 产品信息
商品描述
靶点-Target
Endo180
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
167kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MRC2. AA range:121-170
特异性
Endo180 Polyclonal Antibody detects endogenous levels of Endo180 protein.
基因名称
MRC2
蛋白名称
C-type mannose receptor 2
别名
MRC2;CLEC13E;ENDO180;KIAA0709;UPARAP;C-type mannose receptor 2;C-type lectin domain family 13 member E;Endocytic receptor 180;Macrophage mannose receptor 2;Urokinase-type plasminogen activator receptor-associated protein;UPAR-asso
Organism-1
Human
基因ID-1
9902
SwissProt-1
Q9UBG0
Organism-2
Mouse
基因ID-2
17534
SwissProt-2
Q64449
Organism-3
Rat
基因ID-3
498011
SwissProt-3
Q4TU93
背景
mannose receptor C type 2(MRC2) Homo sapiens This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012],
细胞定位
Membrane; Single-pass type I membrane protein.





