FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Emp
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAEA. AA range:181-230
特异性
Emp Polyclonal Antibody detects endogenous levels of Emp protein.
基因名称
MAEA
蛋白名称
Macrophage erythroblast attacher
别名
MAEA;EMP;HLC10;PIG5;Macrophage erythroblast attacher;Cell proliferation-inducing gene 5 protein;Erythroblast macrophage protein;Human lung cancer oncogene 10 protein;HLC-10
Organism-1
Human
基因ID-1
10296
SwissProt-1
Q7L5Y9
Organism-2
Mouse
基因ID-2
59003
SwissProt-2
Q4VC33
Organism-3
Rat
基因ID-3
298982
SwissProt-3
Q5RKJ1
背景
This gene encodes a protein that mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. The encoded protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix . Cell membrane . Cytoplasm, cytoskeleton . Detected in a nuclear, speckled-like pattern (PubMed:16510120). Localized with condensed chromatin at prophase; Detected in nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis (PubMed:16510120). Present in cytoplasm, nuclear matrix and at the cell surface in macrophages; predominantly nuclear in immature macrophages and predominantly detected at the cell surface in mature macrophages. Colocalizes with F-actin in macrophages (By similarity). .
