Elongin A1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2613915

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Elongin A1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    87kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TCEB3. AA range:131-180

  • 特异性

    Elongin A1 Polyclonal Antibody detects endogenous levels of Elongin A1 protein.

  • 基因名称

    TCEB3

  • 蛋白名称

    Transcription elongation factor B polypeptide 3

  • 别名

    TCEB3;MSTP059;Transcription elongation factor B polypeptide 3;Elongin 110 kDa subunit;Elongin-A;EloA;RNA polymerase II transcription factor SIII subunit A1;SIII p110

  • Organism-1

    Human

  • 基因ID-1

    6924

  • SwissProt-1

    Q14241

  • Organism-2

    Mouse

  • 基因ID-2

    27224

  • SwissProt-2

    Q8CB77

  • Organism-3

    Rat

  • SwissProt-3

    Q63187

  • 背景

    This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus .