- 产品信息
商品描述
靶点-Target
eIF5B
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
139kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EIF5B. AA range:1051-1100
特异性
eIF5B Polyclonal Antibody detects endogenous levels of eIF5B protein.
基因名称
EIF5B
蛋白名称
Eukaryotic translation initiation factor 5B
别名
EIF5B;IF2;KIAA0741;Eukaryotic translation initiation factor 5B;eIF-5B;Translation initiation factor IF-2
Organism-1
Human
基因ID-1
9669
SwissProt-1
O60841
Organism-2
Mouse
基因ID-2
226982
SwissProt-2
Q05D44
Organism-3
Rat
基因ID-3
308306
SwissProt-3
B2GUV7
背景
Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .





