- 产品信息
商品描述
靶点-Target
EF-G2
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
87kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GFM2. AA range:441-490
特异性
EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.
基因名称
GFM2
蛋白名称
Ribosome-releasing factor 2 mitochondrial
别名
GFM2;EFG2;MSTP027;Ribosome-releasing factor 2;mitochondrial;RRF2mt;Elongation factor G 2, mitochondrial;EF-G2mt;mEF-G 2;Elongation factor G2;hEFG2
Organism-1
Human
基因ID-1
84340
SwissProt-1
Q969S9
Organism-2
Mouse
SwissProt-2
Q8R2Q4
背景
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013],
细胞定位
Mitochondrion .





