FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EDG-2
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EDG2. AA range:5-54
特异性
EDG-2 Polyclonal Antibody detects endogenous levels of EDG-2 protein.
基因名称
LPAR1
蛋白名称
Lysophosphatidic acid receptor 1
别名
LPAR1;EDG2;LPA1;Lysophosphatidic acid receptor 1;LPA receptor 1;LPA-1;Lysophosphatidic acid receptor Edg-2
Organism-1
Human
基因ID-1
1902
SwissProt-1
Q92633
Organism-2
Mouse
SwissProt-2
P61793
Organism-3
Rat
基因ID-3
116744
SwissProt-3
P61794
背景
lysophosphatidic acid receptor 1(LPAR1) Homo sapiens The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008],
细胞定位
Cell surface . Cell membrane ; Multi-pass membrane protein . Endosome . Prior to LPA treatment found predominantly at the cell surface. Internalized after LPA treatment. Colocalizes with RALA in endocytic vesicles after LPA treatment. .
